Life Science

Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CRS-8 ISS space mission- The SPHEROIDS project

3D-cell culture: human endothelia cells where sent to ISS in an automated cell culture experiment, to investigate the formation of three dimensional structures in micro gravity. Feeding of the cells with cell culture medium and fixation at the end of the experiment was done using a micro annular gear pump mzr-2921 of the low pressure series.

Jessica Pietsch, Samuel Gass, Stefano Nebuloni, David Echegoyen, Stefan Riwaldt, Christin Baake, Johann Bauer, Thomas J. Corydon, Marcel Egli, Manfred Infanger, Daniel Grimm
Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CRS-8 ISS space mission- The SPHEROIDS project
Biomaterials 124 (2017) 126-156
Publication date: 07.02.2017
http://dx.doi.org/10.1016/j.biomaterials.2017.02.005​​​​​​​

• Figure: Cell culture chamber with pump mzr-2921​​​​​​​

Constant sheath flow in flow cytometry

Low-pulsation liquid flows and low-shear pumping are important prerequisites for use in this field of application. Micro annular gear pumps of the low-pressure series are used both for creating the sheath flow in the range from 1 to 10 ml/min and for cell and particle suspensions. > read more

Analytical instrumentation

Innovative pipetting robot for laboratory applications and OEM integration. With their excellent precision micro annular gear pumps allow pipetting volume 1 µl to 1 ml using the same pump. > read more

Sample preparation for analytics

Integration of micro annular gear pumps allows automated sample preparation for a variety of analytical applications. Liquid handling with 2-4 channels and dosing volumes of 5 µl to 100 ml as well as pipetting in the range of 5 µl to 10 ml are possible. > read more

Micro pumps for chromatography

Micro annular gear pumps of the hermetic inert series are integrated in chromatography systems for purification od APIs, biomolecules and polypeptides. Their high chemical resistance and high precision delivering solvents are very important in this application. > read more